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. 2015 May 5;5:10030. doi: 10.1038/srep10030

Table 1. Clinical data of follow-up patients diagnosed with EAML (n = 43).

Baseline data
 Gender male/female=25/18
 Mean age/years 38.4 (24–76)
 Max diameter ≤4cm: n=29; 4–7 cm: n=4; 7–10 cm: n=7; ≥10 cm: n=3
 percentage of epithelioid cells >90%: n=6; 70–90%: n=9; 5%~70%: n=28. mean: 43.8±22.2
 percentage of atypia cells >90%: n=2; 70–90%: n=5 ; 5%~70%: n=36. mean: 28.4±23.1
 Degree of atypia severe: n=4; moderate: n=10; low: n=29
 Necrosis prominent: 21; focal: 16; little: 6
 Associated symptoms/signs backaches: n=6; hematuria: n=2; without: n=35
   
Involvement range
confined to kidney(n=35) Right: n=19 left: n=16
beyond kidney (n=6) perinephric fat: n=3; renal vein: n=2; infraphrenic postcava: n=1
distant metastasis(n=2) liver: n=1; bowel: n=1
 tumor embolus (+) for 3 cases (1 in infraphrenic postcava; 2 in renal vein)
 Lymph nodes metastasis renal hilus node: n=1; renal hilus and para-aortic nodes: n=1
 Distant metastasis liver: n=1; bowel: n=1
 Surgical method radical nephrectomy: n=12; nephron-sparing surgery: n=30;radical nephrectomy + removal of tumor thrombus in postcava: n=1
   
IHC stain
HMB-45$ 39 (+); 4(focal +)
Ki-67& 10 (+, 2–10%); 28 (−); 5 (unclear)
S100 40 (−); 3 (unclear)
   
Follow-up data
 Follow up duration/month 44.3 (4−71)
 survival status alive : n=41; dead: n=2
 Recurrence One patient with renal hilus node metastasis at baseline suffered local recurrence 10 months postoperatively and died from serious cancer cachexia 4 months later
 Metastasis One patient suffered metastasis to the liver and lung 12 mons postoperatively and died 17 months after metastasis

$HMB-45 is a monoclonal antibody that reacts against an antigen present in melanocytic tumors such as melanomas, and means Human Melanoma Black.

&KI-67 is a nuclear protein that is associated with and may be necessary for cellular proliferation.

S100 is a kind of melanoma marker.