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Scheme of the Arabidopsis core clockwork. In the central loop LHY and CCA1 on the one hand and TOC1 on the other hand reciprocally repress their own expression. In the morning loop, LHY and CCA1 activate PRR9 and PRR7 which in turn repress CCA1 and LHY. PRR7 and PRR9 expression is switched off during the night through the EC consisting of LUX, EFL3, and ELF4. In the evening loop, the EC and TOC1 reciprocally regulate their expression.
