Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Non-nitrogen/nitrogen-containing bisphosphonates grouped according to their potency. Structures of the R1 and R2 side chains.
| Potency | Biphosphonate | R1 | R2 | |
|---|---|---|---|---|
| Non-nitrogen-containing biphosphonates | 1x | Etidronate | -OH | -CH3 |
| 10x | Chlodronate | -Cl | -Cl | |
| Nitrogen-containing biphosphonates | 100x | Pamidronate | -OH | -(CH2)2-NH2 |
| >100 <1000 |
Alendronate | -OH >1000 |
-(CH2)3-NH2 | |
| >1000 <10,000 |
Risendronate | -OH |  |
|
| >10,000 | Zoledronate | -OH |  |
