Table 3.
Summary of the cases of epithelioid hemangioendothelioma of other sites in the current literature.
| Author/Reference | No. | Gender M/F | Age at detection | Tumor site | Therapy spread | Metastatic | Survival years | Clinical presentation |
|---|---|---|---|---|---|---|---|---|
| Wong2 | 1 | 0/1 | 50 | Subcutaneous fat of forehead-left orbit-left frontal sinus | Surgery | Frontal bone | Not stated | Red-colored nodular skin lesions Visual disturbance |
| Mukherjee10 | 2 | 1/1 | 20 | Anterior abdominal wall | Not stated | None | Not stated | Painful anterior abdominal wall swelling Palpable mass Enlargement of right tonsil |
| Drazin47 | 1 | 1/0 | 62 | Mastoid bone | Surgery Radiation | None | 8 years (alive) | Positional vertigo Hearing loss Mild mass effect upon the 4th ventricle |
| Ma49 | 1 | 0/1 | 58 | Clival region | Surgery | None | Not stated | Pain of the forehead Visual deterioration |
| Kerry51 | 1 | 1/0 | 25 | D7 | Surgery Adjuvant radiation CHT (doxorubicin) | Lymph nodular and cutaneous | 8 weeks | Severe back pain Paraplegia |
| Iimuro53 | 1 | 0/1 | 48 | Retroperitoneum | Surgery | Regional and Virchow’s lymph nodes | 13 months | Slight discomfort in lower right abdomen |
| Illueca54 | 1 | 0/1 | 20 | Ovary | Surgery | None | 1 year | Pelvic pain |
| Iyer55 | 1 | 1/0 | 69 | Prostate | - | Seminal vescicles Periprostatic extension | Not stated | Perineal pain night sweats rectal fullness increased urinary frequency urgency |
| Al-Faky56 | 1 | 0/1 | 27 | Eyelid | Surgery | None | Not stated | Eyelid swelling |
| Gomez-Arellano57 | 1 | 1/0 | 19 | D1,D3,D4 | Palliative radiation | Lung Pleura | 5 months | Back pain Paresthesia Loss of strength of lower limbs Pathologic fracture Paraplegia |
| de Singly58 | 1 | 1/0 | 78 | D9 | Surgery | Colonic metastases | Periumbilical pain Weight loss General condition alteration |
|
| Larochelle60 | 1 | 1/0 | 57 | Right ankle-tibia-talus | Surgery | None | Not stated | Right ankle pain Surrounding edematous bone reaction |
| Gherman61 | 1 | 1/0 | 24 | Forearm | Surgery | None | 24 months | Pain Weakness Oval palpable mass |
| Vidya62 | 1 | 0/1 | 16 | Skin of the right lower limb | Surgery | None | Not stated | Swelling Erythematous skin lesions |
| Kim63 | 1 | 1/0 | 47 | Liver | Liver transplantation | Infraioid neck | Not stated | Blood count alteration |
| Aquilina64 | 2 | 2/0 | 38.5 | C2-4, D10 | Surgery Radiation CHT (ifosfamide+carboplatin+etoposide+vincristine) |
None | Not stated | Nocturnal thoracic low-back pain Neck pain |
| Pinet65 | 1 | 0/1 | 50 | Parietal pleura | CHT (carboplatin +etoposide) | Peritoneum | Not stated (complete remission 18 months after CHT) | Right pleural effusion Contralateral pleural effusion Chylous ascites |
| Kleck66 | 1 | 1/0 | 61 | Right distal humerus | Surgery | Two local lymph nodes and an ipsilateral axillary lymph node | Not stated Swelling Palpable mass |
Severe pain Limited range of motion Decreased strength Pathological fracture |
| Rosenthal67 | 1 | 0/1 | 21 | Left foot and mid-leg | RF ablation surgery | Left distal femur Left medial foot Distal left tibia Left 2nd metatarsal |
6 years | Left foot and tibial pain |
| Kabukcuoglu68 | 1 | 0/1 | 48 | 1st metatarsal | Surgery | None | 4 years | No symptoms |
| Sardaro69 | 1 | 0/1 | 46 | Multiple disseminated pleuropulmonary nodules | Surgery Radiation CHT (ifosfamide+epirubicin) |
L3-L4 Spleen | 11 months | Back pain |
CHT, chemotherapy; RF, radio frequency.