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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Leuk Lymphoma. 2014 Feb 17;55(9):2079–2084. doi: 10.3109/10428194.2013.869801

Figure 1. Lymph node Histology in CLL.

Figure 1

Proliferation centers characterized by paraimmunoblasts (prolymphocytes) are a characteristic feature of lymph nodes involved by CLL. Prominent proliferation centers with >40% paraimmunoblasts are shown in sections A to C. In section B there is a more subtle increase in paraimmunoblasts interspersed with small CLL lymphocytes. D: Example of a more typical appearance of CLL with a predominance of small lymphocytes and foci of proliferation center formation. (H&E stain, Nikon objective 20x lens with 200x magnification, Olympus DP controller and Nikon Eclipse 80i camera)