Table 2.
Standardized incidence ratios of secondary malignancy in patients diagnosed with primary clinically localized CAP, stratified by follow-up intervals after diagnosis of primary malignancy. Bold typeface indicates p<0.05.
Time after diagnosis of primary malignancy | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
2–11 months | 12–59 months | 60–119 months | ≥120 months | Total | ||||||
Obs/Exp | SIR (95% CI) | Obs/Exp | SIR (95% CI) | Obs/Exp | SIR (95% CI) | Obs/Exp | SIR (95% CI) | Obs/Exp | SIR (95% CI) | |
Thyroid | 54/29.5 | 1.83 (1.4–2.4) | 146/118 | 1.24 (1.0–1.5) | 109/87 | 1.25 (1.0–1.5) | 29/26 | 1.11 (0.7–1.6) | 338/261 | 1.30 (1.2–1.4) |
Kidney | 399/160 | 2.49 (2.3–2.8) | 712/653 | 1.09 (1.01–1.17) | 534/491 | 1.09 (1–1.2) | 177/152 | 1.16 (1–1.4) | 1822/1457 | 1.25 (1.19–1.31) |
Urinary Bladder | 552/390 | 1.41 (1.3–1.5) | 1812/1673 | 1.08 (1.03–1.13) | 1401/1360 | 1.03 (0.98–1.09) | 523/466 | 1.12 (1.0–1.2) | 4288/3891 | 1.10 (1.07–1.14) |
Colorectal | 595/592 | 1.01 (0.9–1.1) | 2308/2384 | 0.97 (0.93–1.01) | 1507/1718 | 0.88 (0.83–0.92) | 478/530 | 0.90 (0.8–0.99) | 4888/5223 | 0.94 (0.91–0.96) |
Lung and Bronchus | 767/849 | 0.90 (0.84–.097) | 2717/3446 | 0.79 (0.76–0.82) | 2075/2550 | 0.81 (0.78–0.85) | 631/803 | 0.79 (0.73–0.85) | 6190/7648 | 0.81 (0.79–0.83) |
Esophagus | 72/82 | 0.88 (0.69–1.11) | 262/332 | 0.79 (0.7–0.89) | 221/246 | 0.9 (0.79–1.03) | 64/76 | 0.84 (0.65–1.08) | 619/736 | 0.84 (0.78–0.91) |
Pancreas | 132/140 | 0.95 (0.8–1.1) | 561/586 | 0.96 (0.88–1.0) | 407/464 | 0.88 (0.79–0.97) | 147/156 | 0.95 (0.8–1.11) | 1247/1345 | 0.93 (0.88–0.98) |
Hodgkin’s Lymphoma | 16/12 | 1.37 (0.8–2.2) | 37/46 | 0.8 (0.6–1.1) | 32/33 | 0.97 (0.66–1.4) | 7/10 | 0.68 (0.3–1.4) | 92/101 | 0.91 (0.73–1.12) |
Non-Hodgkin’s Lymphoma | 284/213 | 1.34 (1.2–1.5) | 871/887 | 0.98 (0.92–1.1) | 706/692 | 1.02 (0.95–1.1) | 226/227 | 0.99 (0.87–1.1) | 2087/2019 | 1.03 (0.99–1.08) |
Leukemia | 133/150 | 0.88 (0.74–1.1) | 545/633 | 0.86 (0.79–0.94) | 476/500 | 0.95 (0.87–1.04) | 184/168 | 1.09 (0.94–1.26) | 1338/1451 | 0.92 (0.87–0.97) |