Fig. 6.—

Intrinsic characteristics of mRNAs. (A) Average poly(A) tail length of transcripts of each chromosome. A, average poly(A) tail length of transcripts of all autosomes. X, average poly(A) tail length of transcripts of the X-chromosome. Error bars indicate 95% confidence intervals. (B) Gene scatterplot of poly(A) tail length versus half-life. Each dot represents one gene. (C) Chromosomal average of GC and GC3 contents of all CDS of the human genome (black and gray bars, respectively): 86,390 in total, including 2,585 situated on the X-chromosome. (D) Position of each chromosome along the first and second principal components obtained from a PCA of the 3′-UTR sequences of human genes.