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. Author manuscript; available in PMC: 2016 Apr 4.
Published in final edited form as: Lancet. 2014 Dec 11;385(9975):1324–1332. doi: 10.1016/S0140-6736(14)61731-1

Table 2.

Effect of vitamin A on endpoints

Vitamin A group Placebo group Risk per 1000 in vitamin A group Risk per 1000 in placebo group Risk difference per 1000 (95% CI) Risk ratio (95% CI) p value
Events Newborns Events Newborns
Mortality at 6 months (n=30 892)
Overall 407 15 428 372 15 464 26·38 24·06 2·32 (−1·17 to 5·82) 1·10 (0·95 to 1·26) 0·193
Boys 233 8135 215 8070 28·64 26·64 2·00 (−3·05 to 7·05) 1·08 (0·90 to 1·29) 0·438
Girls 174 7291 157 7392 23·87 21·24 2·63 (−2·18 to 7·43) 1·12 (0·91 to 1·39) 0·284
Interaction with sex ·· ·· ·· ·· ·· ·· ·· ·· 0·760
Neonatal mortality (n=31 387)
Overall 213 15 677 206 15 710 13·59 13·11 0·47 (−2·07 to 3·01) 1·04 (0·86 to 1·25) 0·714
Boys 124 8273 124 8198 14·99 15·13 −0·14 (−3·86 to 3·58) 0·99 (0·77 to 1·27) 0·942
Girls 89 7402 82 7510 12·02 10·92 1·11 (−2·31 to 4·52) 1·10 (0·82 to 1·48) 0·526
Interaction with sex ·· ·· ·· ·· ·· ·· ·· ·· 0·594
Mortality at 12 months (n=29 435)
Overall 566 14 686 546 14 749 39 37 1·52 (−2·84 to 5·88) 1·04 (0·93 to 1·17) 0·494
Boys 312 7745 324 7713 40 42 −1·72 (−7·99 to 4·54) 0·96 (0·82 to 1·12) 0·590
Girls 254 6939 222 7034 37 32 5·04 (−0·97 to 11·06) 1·16 (0·97 to 1·38) 0·100
Interaction with sex ·· ·· ·· ·· ·· ·· ·· ·· 0·111
Hospital admission up to 6 months (n=30 895)
Overall 332 15 429 303 15 466 21·52 19·59 1·93 (−1·24 to 5·09) 1·10 (0·94 to 1·28) 0·233
Boys 194 8135 166 8072 23·85 20·56 3·28 (−1·25 to 7·82) 1·16 (0·94 to 1·42) 0·156
Girls 138 7292 137 7392 18·92 18·53 0·39 (−3·99 to 4·78) 1·02 (0·81 to 1·29) 0·861
Interaction with sex ·· ·· ·· ·· ·· ·· ·· ·· 0·422

All event rates given over participants not lost to follow-up before end of risk period.