Table 3.
Univariable and multivariable associations of demographics and psychosocial measures and willingness-to-pay, Model 2: Willing-to-Pay High ($500–$2000) v. Low ($25–$200)
| Willing to pay $500–$2000 for GT (n=115) | Willing to pay $25–$200 for GT (n=156) | Univariable, Willing to Pay High vs. Low | Multivariable, n=255 with complete responses | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
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| Range | N | Percent | N | Percent | OR | 95% CI | p-value* | OR | 95% CI | p-value* | |
| Gender | Female | 75 | 65.2 | 122 | 78.2 | 1.00 | Reference | 1.00 | Reference | 0.0095 | |
| Male | 40 | 34.8 | 34 | 21.8 | 1.91 | 1.12–3.28 | 0.019 | 2.31 | 1.23–4.36 | ||
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| Education | <High School | 9 | 8.0 | 26 | 16.8 | 1.00 | Reference | 1.00 | Reference | ||
| Some College | 28 | 25.0 | 53 | 34.2 | 1.53 | 0.63–3.70 | 0.35 | 1.99 | 0.71–5.57 | 0.19 | |
| College | 43 | 38.4 | 45 | 29.0 | 2.76 | 1.16–6.56 | 0.022 | 3.43 | 1.27–9.30 | 0.015 | |
| Graduate School | 32 | 28.6 | 31 | 20.0 | 2.98 | 1.21–7.37 | 0.018 | 2.6 | 0.92–7.37 | 0.071 | |
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| First degree relatives with colorectal cancer | 0 | 53 | 46.1 | 59 | 38.1 | 1.00 | Reference | 1.00 | Reference | ||
| 1 | 56 | 48.7 | 71 | 45.8 | 0.88 | 0.53–1.46 | 0.62 | 0.74 | 0.41–1.34 | 0.31 | |
| 2+ | 6 | 5.2 | 25 | 16.1 | 0.27 | 0.10–0.70 | 0.0074 | 0.23 | 0.07–0.71 | 0.011 | |
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| Reasons for Not Screening Checklist Score | 0 | 60 | 52.2 | 81 | 51.9 | 0.76 | 0.44–1.31 | 0.32 | 0.85 | 0.45–1.59 | 0.60 |
| 1 | 41 | 35.7 | 42 | 26.9 | 1.00 | Reference | 1.00 | Reference | |||
| 2+ | 14 | 12.2 | 33 | 21.2 | 0.44 | 0.20–0.93 | 0.031 | 0.5 | 0.21–1.20 | 0.12 | |
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| Psychosocial Measures, continuous variables | N* | Mean (SD) | N* | Mean (SD) | OR | 95% CI | p-value | OR | 95% CI | p-value | |
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| Reasons for wanting GT | [0–11] | 115 | 6.5 (2.0) | 156 | 6.0 (1.9) | 1.14 | 1.01–1.30 | 0.043 | 1.15 | 0.98–1.35 | 0.088 |
| Reasons for not wanting GT | [0–10] | 115 | 0.9 (1.6) | 156 | 1.4 (1.9) | 0.84 | 0.72–0.98 | 0.027 | 0.82 | 0.68–0.99 | 0.043 |
| Barriers to CRC screening | [11–55] | 115 | 20.0 (5.3) | 152 | 21.4 (6.0) | 0.96 | 0.92–1.00 | 0.061 | 1.01 | 0.92–1.11 | 0.88 |
| N | Percent | N | Percent | OR | 95% CI | p-value | OR | 95% CI | p-value | ||
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| Worry about developing a gastrointestinal cancer | Never | 25 | 219 | 47 | 30.9 | 1.00 | Reference | 1.00 | Reference | ||
| Sometimes | 53 | 46.5 | 60 | 39.5 | 1.66 | 0.90–3.06 | 0.100 | 1.21 | 0.58–2.56 | 0.61 | |
| Often | 16 | 14 | 30 | 19.7 | 1.00 | 0.46–2.18 | 0.99 | 0.45 | 1.15–9.52 | 0.13 | |
| A lot | 20 | 17.5 | 15 | 9.9 | 2.51 | 1.10–5.73 | 0.029 | 0.9 | 0.26–3.04 | 0.86 | |
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| Worry affects your mood | Never | 56 | 49.6 | 107 | 70.9 | 1.00 | Reference | 1.00 | Reference | ||
| Sometimes | 40 | 35.4 | 30 | 19.9 | 2.55 | 1.44–4.52 | 0.0014 | 3.26 | 1.51–7.02 | 0.0025 | |
| Often | 10 | 8.9 | 10 | 6.6 | 1.91 | 0.75–4.86 | 0.17 | 2.40 | 0.72–7.94 | 0.153 | |
| A lot | 7 | 6.2 | 4 | 2.7 | 3.34 | 0.94–11.91 | 0.063 | 3.64 | 0.64–20.73 | 0.146 | |
Abbreviations: CI, confidence interval; CRC, colorectal cancer; GT, genetic testing; OR, odds ratio; SD, standard deviation
*
p-values are pairwise comparisons versus reference group, and from logistic regression models, Wald Chi-square tests
Missing values, excluded from tests: Education, n=4; First degree relatives, n=1; Worry develop cancer, n=5; worry affect mood, n=7; barriers to CRC screening, n=4