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. 2015 May 5;10(5):e0121340. doi: 10.1371/journal.pone.0121340

Table 3. Complete-case cost-effectiveness analysis (mean cost in £ / mean QALY, 95% CI).

Intervention (127 patients) Standard care (127 patients) Incremental cost / QALYs gained
The cost of care a 4114 (3417, 4956) 4085 (3145, 5297) 29 (-1386, 1333)
The cost of care—adjusted b 4139 (4004, 4289) 4103 (3969, 4252) 36 (-159, 232)
The intervention cost 199 (178, 217) 0 199 (178, 217)
Total cost (care cost + intervention cost) 4312 (3612, 5153) 4085 (3145, 5297) 228 (-1203, 1527)
Total cost—adjusted (care cost adjusted + intervention cost) 4338 (4187, 4490) 4103 (3957, 4249) 235 (21, 445)
QALYs gained 0.120 (0.108, 0.133) 0.117 (0.105, 0.129) 0.004 (-0.012, 0.020)
QALYs gained—adjusted c 0.125 (0.120, 0.131) 0.123 (0.117, 0.129) 0.002 (-0.006, 0.011)
ICER £63 559/QALY
ICER adjusted £116 326/QALY d

aInpatient, day-case and outpatient cost data were collected for both locations, Nottingham and Leicester.

bAdjusted by age, sex, hospital location (Leicester), and baseline utility, permanent care home residence, Charlson co-morbidity (scores 2–3 and ≥4), and higher risk of future health problems at admission (≥4 on Identification of Senior at Risk (ISAR) tool). A GLM model (family—gamma, link—0.45) was applied.

cOLS was applied (adjustment covariates as above, except care home residence at baseline).

dFrom CEAC (Fig 1) we know that 95% CI for ICER is £13,900-.