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. 2015 May 5;10(5):e0125075. doi: 10.1371/journal.pone.0125075

Fig 5. Granuloma area reduction and representative granulomas of mice immunized with the DNA vaccines and challenged with S. mansoni cercariae.

Fig 5

(A) Graph showing the granuloma area in liver of vaccinated mice. Representative granulomas of (B) pUMVC3; (C) pUMVC3/Sm29; (D) pUMVC3/TSP-2; (E) pUMVC3/Chimera; (F) pUMVC3/Sm29 + pUMVC3/TSP-2 are demonstrated. The scale bar corresponds to 50 μm. Significant differences from mice immunized with the pUMVC3 control are denoted by an asterisk (*) for p<0.05, and the percent reductions are shown.