Table 1. Protection level induced by DNA immunization.
| First trial a | Worms recovered ± SD | % of protection |
|---|---|---|
| pUMVC3 | 79.3 ± 4.8 | - |
| pUMVC3/Sm29 | 65.8 ± 4.5 | 17 * |
| pUMVC3/TSP-2 | 61.9 ± 2.8 | 22 * |
| pUMVC3/Chimera | 54.7 ± 5.8 | 31 * # |
| pUMVC3/Sm29 + pUMVC3/TSP-2 | 60.3 ± 5.8 | 24 * |
| Second trial a | ||
| pUMVC3 | 45.0 ± 7.8 | - |
| pUMVC3/Sm29 | 34.9 ± 5.2 | 22 * |
| pUMVC3/TSP-2 | 35.1 ± 7.0 | 22 * |
| pUMVC3/Chimera | 30.7 ± 6.9 | 32 * |
| pUMVC3/Sm29 + pUMVC3/TSP-2 | 30.5 ± 5.9 | 32* |
* p<0.05 compared to pUMVC3 control
# p<0.05 compared to pUMVC3/Sm29
a Ten animals per group in each independent experiment