. 2015 May 5;10(5):e0125363. doi: 10.1371/journal.pone.0125363

Table 4. Microbiology data.

	1^st Dose	24hr Post Dose	Change(n = 13)	P Value^**
	Descriptive Statistics^*	Descriptive Statistics	Change(n = 13)	P Value^**
	N, Mean (SD), Median (25%, 75%)	N, Mean (SD), Median (25%, 75%)	Diff (SE)
Rectal Microflora Cultures (Anaerobic)
*Bacteriodes fragilis*
RGVF: 1^st Dose vs. 24hr Post Dose	13, 2.2 (1.6), 2 (1, 4)	13, 3.2 (1.1), 3 (3, 4)	1.05 (0.53)	0.0460
HEC/VF: 1^st Dose vs. 24hr Post Dose	12, 3.1 (0.7), 3 (3, 3.5)	12, 2.1 (1.2), 2 (2, 3)	-0.99 (0.32)	0.0018
Change at 24hr Post Dose (RGVF v HEC/VF)			2.04 (0.73)	0.0051
Rectal Microflora Cultures (Facultative Isolates)
Lactobacillus, H2O2 negative
RF: 1^st Dose vs. 24hr Post Dose	12, 0.8 (1.1), 0 (0, 2)	12, 0.3 (0.6), 0 (0, 0)	-0.57 (0.26)	0.0325
Change at 24hr Post Dose (RF v HEC/VF)			-0.74 (0.24)	0.0023
Gram positive rods, other
RF: 1^st Dose vs. 24hr Post Dose	12, 2.0 (1.1), 2 (1, 3)	12, 1.4 (1.3), 2 (0, 2.5)	-0.68 (0.34)	0.0422
Viridans streptococcus, H2O2-positive
HEC/VF: 1^st Dose vs. 24hr Post Dose	12, 1.3 (1.4), 1.5 (0, 2)	12, 0.8 (1.2), 0 (0, 1.5)	-0.50 (0.20)	0.0110
*Escherichia coli*
Change at 24hr Post Dose (RF v HEC/VF)			-0.98 (0.39)	0.0117

*Semi-quantitative score (0 = no growth; 4 = 10⁷ colony forming units/mL)

** P-value from significance test of relevant contrast from GEE model.