Table 4. Meta-analysis of IFITM3-SNP rs12252 and severity of influenza (C vs. T).
Comparison | OR(95%CI) | P | Heterogeneity of study design | Effect modle | Test of publication | |||
---|---|---|---|---|---|---|---|---|
bias | ||||||||
Z | P het | I 2 % | t value | P value | ||||
Severe vs Mild | 2.37 [1.32, 4.25] | 0.004* | 2.90 | 0.06 | 71 | R | 0 | 1 |
Mild vs Control | 1.26 [0.93, 1.71] | 0.13 | 1.50 | 0.97 | 0 | F | 0 | 1 |
Severe vs Control | 2.70 [1.85, 3.94] | < 0.000* | 5.14 | 0.16 | 42 | F | 0.34 | 0.734 |
OR, odds ratio; CI, confidence interval; F, fixed-effect model; R, random-effect model; P het, P value of heterogeneity.
* P<0.05 stands for significance.