Table 3. miRNA-mRNA pairs found inversely correlated and validated in the literature.
| miRNA | Known Target | Reference |
|---|---|---|
| Up-regulated miRNAs/Down-regulated targets | ||
| let-7i-5p | ATAD3B, BCL2L1, CCND1, CDIPT, DUSP23, FAM105A, F2, GAK, GPR56, GYS1, MARS2, POLD2, POM121/POM121C, RHOB, RHOG, TAGLN | Selbach et al., 2009 (Nature) |
| miR-29c-3p | COL1A1, DUSP2, GPR37, KLF4, LOXL2, MAPRE2, MYBL2, TGFB3 | Li et al., 2009 (J Biol Chem) |
| miR-146b-5p | IRAK2, NOVA1, PTGES2, SYT1 | Hou et al. 2009 (J Immunol) |
| miR-503-5p | CCND1 | Jiang et al., 2009 (BMC Cancer) |
| miR-485-5p | MDM2 | Ratoviski et al., 2014 (Cell Cycle) |
| miR-708-5p | CASP2 | Song et al., 2013 (J Cancer Res Clin Oncol) |
| Down-regulated miRNAs/Up-regulated targets | ||
| miR-129-5p | TNPO1 | Dyrskjot et al., 2009 (Cancer Res) |
| miR-205-5p | ZEB1 | Gregory et al., 2008 (Nat Cell Biology) |
| miR-409-3p | FGB, RDX | Fort et al. 2010 (Blood) |
This table shows the association between miRNAs and mRNAs that were significantly dysregulated in SLKK cells compared to SLK cells. Only the miRNA-mRNA pairs experimentally validated in the literature are shown here. The majority of the targets were identified through IPA-integrated TarBase v5.0 and others independently.