Table 3. Clinical characteristics between intravenous GCV and oral VGCV.
Intravenous GCV (n = 61) | Oral VGCV (n = 22) | P-value | |
---|---|---|---|
White blood cells (/ul) | 6,550 (1,280–27,360) | 7,430 (2,410–14,750) | 0.871 |
Hemoglobin (g/dL) | 9.1 (4.0–15.9) | 10.8 (8.2–14.1) | 0.003 |
Platelet (/ul) | 108,500 (21,000–465,000) | 155,000 (39,000–329,000) | 0.321 |
Lymphocyte (%) | 5.9 (1.4–22.4) | 5.7 (2.1–48.9) | 0.662 |
INR | 1.17 (0.93–5.51) | 1.11 (0.98–1.21) | 0.065 |
Albumin (g/dL) | 3.1 (2.5–3.9) | 3.2 (2.9–3.9) | 0.140 |
Total bilirubin (mg/dL) | 2.2 (0.4–14.0) | 0.7 (0.3–2.1) | <0.001 |
AST (IU/L) | 34 (11–445) | 21 (11–37) | 0.008 |
ALT (IU/L) | 87 (15–959) | 30 (15–277) | 0.016 |
ALP (IU/L) | 92 (39–391) | 86 (35–121) | 0.072 |
Creatinine (mg/dL) | 0.98 (0.25–4.13) | 0.82 (0.35–2.17) | 0.137 |
Concentration of FK506 (ng/mL) | 6.6 (0.5–16.7) | 6.2 (1.4–10.8) | 0.586 |
Time from LT to CMV infection (days) | 21 (1–221) | 30 (9–53) | 0.001 |
Highest titer of CMV antigenemia | 22 (10–462) | 24 (12–754) | 0.313 |
Duration of antiviral agents use (days) | 12 (8–27) | 16 (14–21) | 0.076 |
GCV, ganciclovir; VGCV, valganciclovir; AST, aspartate transaminase; ALT, alanine transaminase; ALP, alkaline phosphatase; LT, liver transplantation; CMV, cytomegalovirus