Figure 3.

(A) Cartoon representation of OspG-E2∼Ub complexes. The UbcH5 and UbcH7 complexes are superimposed and are nearly identical. OspG is painted wheat, UbcH5/7 is green and Ub is blue. The darker shades show the UbcH7 complex; (B) the OspG-Ub interface. The OspG is shown as molecular surface colored wheat with gray marking hydrophobic residues. The Ub faces OspG with the Ile44 side and inserts a loop culminating with GlyXX into a deep depression in OspG surface; (C) the UbcH7 residue contacting OspG surface. Phe63 plays a key role in these interactions. An interactive view is available in the electronic version of the article.