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. 2015 Mar 16;24(5):812–822. doi: 10.1002/pro.2652

Figure 3.

Figure 3

Cross-species binding experiments (RBP-J + dNICD). Figure shows representative thermograms (raw heat signal and nonlinear least squares fit to the integrated data) for RBP-J binding Drosophila NICD. Each experiment was performed at 25°C, with 40 titrations of 7 μL injections spaced 120 s apart. The experimentally determined dissociation constant (Kd) is shown for each experiment. A: RBP-J binding dRAMANK. B: RBP-J binding dRAM. C: RBP-J does not bind dANK. D: CTD of RBP-J does not bind dANK. NBD, no binding detected.