Table 1.

Calorimetric Data for the Binding of Drosophila NICD to Su(H)

Cell	Syringe	K (M−1)	Kd (µM)	ΔG° (kcal/mol)	ΔH° (kcal/mol)	−TΔS° (kcal/mol)
dRAMANK	Su(H)	1.9 ± 0.9 × 107	0.060	−9.9 ± 0.2	−23.8 ± 0.5	13.9 ± 0.5
Su(H)	dRAM	3.0 ± 0.7 × 106	0.345	−8.8 ± 0.1	−17.4 ± 0.7	8.6 ± 0.9
Su(H)	dANK	1.5 ± 0.4 × 106	0.668	−8.4 ± 0.1	−6.1 ± 0.4	−2.2 ± 0.5
dCTD	dANK	4.7 ± 0.4 × 104	20.9	−6.3 ± 0.05	−9.3 ± 1.0	2.9 ± 1.0

All experiments were performed at 25°C. Values are the mean of at least three independent experiments and errors represent the standard deviation of multiple experiments.