Table 3.

Kyoto Encyclopedia of Genes and Genomes pathways with differentially expressed genes between the two groups

KEGG ID	Pathway name	Gene symbols	C	O	E	R	rawP	adjP
01100	Metabolic pathways	Idi1, Ido2, Chkb, Cyp51, Nsdhl, Cyp2c54, Sds, Nans, Ces3b, Cyp7a1, Asns, Pnliprp1, Sc4 mol, Nnmt, Fdps, Cryl1, Sqle, Ggt6, Cyp2c38, Ces3a, Hsd3b5, Ccbl1, Agpat9, Bdh2, Ldhb, Acss3, Acmsd, Cyp2u1	1184	28	5.4	5.18	1.78E-12	1.16E-10
04630	Jak-STAT signaling pathway	Lepr, Socs2, Irf9, Myc, Pim1, Ccnd1, Cish	153	7	0.7	10	7.31E-06	9.50E-05
03320	PPAR signaling pathway	Cyp7a1, Aqp7, Lpl, Cpt1b	80	4	0.4	11	0.0005	0.0036
00590	Arachidonic acid metabolism	Cyp2c54, Cyp2c38, Ggt6, Cyp2u1	90	4	0.4	9.74	0.0008	0.0047
00561	Glycerolipid metabolism	Agpat9, Lpl, Pnliprp1	51	3	0.2	12.9	0.0017	0.0069
00564	Glycerophospholipid metabolism	Agpat9, Chkb, Gpd2	80	3	0.4	8.22	0.006	0.015
01040	Biosynthesis of unsaturated fatty acids	Acot4, Acot3	25	2	0.1	17.5	0.0058	0.015
04950	Maturity onset diabetes of the young	Hhex, Hes1	26	2	0.1	16.9	0.0063	0.0152
04975	Fat digestion and absorption	Pnliprp1, Apoa4	45	2	0.2	9.74	0.018	0.0355
00591	Linoleic acid metabolism	Cyp2c54, Cyp2c38	46	2	0.2	9.53	0.0188	0.0359
00140	Steroid hormone biosynthesis	Hsd3b5, Cyp7a1	55	2	0.3	7.97	0.0263	0.0442

Fold change >1.5, P < 0.05. adjP, P-value adjusted by the multiple test adjustment; C, the number of reference genes in the category; KEGG, Kyoto Encyclopedia of Genes and Genomes; O, the number of genes in the gene set and category; E, the expected number in the category; R, ratio of enrichment; rawP, P-value from hypergeometric test.