Figure 6.

Aurantiamide acetate inhibited the growth of subcutaneous tumours. U87 cells were inoculated subcutaneously into the right axillary region of the flank of nude mice. Three weeks following inoculation, a 150 μl intratumoural injection of aurantiamide acetate (AA) or the same volume of PBS (Ctrl) was given every 2 days. Drug administration was lasted for 8 days and the tumour size was measured on Day 10. Data were calculated from five animals for each group. (A) Animal body weight (g). (B) Relative tumour size on Day 10. Representative data of gross examination of tumour-bearing mice (C) and tumour tissues (D).