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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Clin Immunol. 2015 Mar 8;158(1):1–7. doi: 10.1016/j.clim.2015.02.014

Table 1. Clinic and phenotypical patient characteristics.

Age/ gender TNMB Stage Flow cytometry features %IL-31+ CD3+/ CD4+/CD26- Functional assay
80sM Stage IVA, T4NXM0B2 CD4:CD8 of 101, discrete subset of CD3+/CD4+/CD26- :61 % (6146 cells/μl) 4.19% Dexamethasone suppression
70sM Stage IVA, T4N0M0B2 CD4:CD8 of 31.3, discrete subset of CD3+/CD4+/CD26-: 87% (9369 cells/μl) 6.32% Dexa/Vorinostat suppression
60sM Stage IVA2 T4N3M0B2 CD4:CD8 of 4.9, discrete subset of CD3+/CD4+/CD26-: 41 % (1020 cells/μl) 12% Vorinostat suppression
50sM Stage IIIB T4NXM0B1 CD4:CD8 of 4.1, discrete subset of CD3+/CD4+/CD26-23% (435 cells/μl) 2.67% Dexamethasone suppression
70sF Stage IVA, T2NXM0B2 CD4:CD8 of 64.2, discrete subset of CD3+/CD4+/CD26-64% (5833 cells/μl) 3.34% Vorinostat suppression
20sM Stage IIIB T4N2M0B1 CD4:CD8 of 4.9, discrete subset of CD3+/CD4+/CD26-30% (164 cells/μl) 1.03% Dexa/Vorinostat suppression
60sM Stage IVA, T2NXM0B2 CD4:CD8 of 22, discrete subset of CD3+/CD4+/CD26-80% (843 cells/μl) 4.73% Anti-CCR4 trial
70sM Stage IVA, T4NXM0B2 CD4:CD8 of 132.9, discrete subset of CD3+/CD4+/CD26- of 96% (33251 cells/μl) 9.17% In vivo Romidepsin
50sM Stage IVA, T4NXM0B2 CD4:CD8 of 30, discrete subset of CD3+/CD4+/CD26- of 91 % (7012 cells/μl) Unknown High IL-31 mRNA expression by PCR In vivo Romidepsin