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. Author manuscript; available in PMC: 2016 May 30.
Published in final edited form as: Stat Med. 2015 Mar 9;34(12):1981–1992. doi: 10.1002/sim.6462

Figure 2.

Figure 2

Empirical type 1 error rate for large sample LRT {solid line (full=black, partial= gray)}, score/log-rank test (dot/dashed line), and Wald test {dashed line (full=black, partial=gray)} as a function of sample size n = N (i.e., N/2 per arm) for p0 = p1 = 0.5 probability of infection per challenge under Scenario 1 (no heterogeneity or immunity) and various values of cmax = Cmax. The dotted horizontal line corresponds to the nominal significance level α = 0.05.