Table 1.
Summery of Runx1 Experimental and Patient Data from Human OA Knees
| Pt # | Age | Gender | Malalignment | Lateral Femur | Medial Femur | Tibia | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Anterior Femur | Posterior Femur | Combined LF | Anterior Femur | Posterior Femur | Combined MF | Lateral Tibia | Medial Tibia | ||||
|
|
|
|
|||||||||
| K1 | 52 | F | Varus | 0.17 (0.1) | 1.37 (0.31) | NC | NC | ||||
| K2 | 81 | F | Varus | 0.92 (0.25) | 0.11 (0.06) | 0.14 (0.05) | 0.50 (0.11) | 0.24 (0.04) | 0.22 (0.08) | 0.52 (0.05) | 0.74 (0.28) |
| K3 | 52 | F | Varus | 0.05 (0.01) | 1.18 (0.2) | 1.71 (0.42) | 1.35 (0.48) | 1.28 (0.11) | 1.60 (0.65) | 0.55 (0.09) | 0.95 (0.09) |
| K4 | 66 | F | Varus | 0.68 (0.09) | 1.24 (0.44) | NC | NC | ||||
| K5 | 64 | F | Varus | 0.01 (0.08) | 0.55 (0.25) | 0.25 (0.08) | 1.18 (0.15) | 1.02 (0.13) | 1.01 (0.51) | 0.44 (0.08) | 0.63 (0.06) |
NC, Not collected. Combined samples of anterior with posterior tissue not separated
Densitometry measurements of Runx1 protein levels by immunoblot are expressed as mean (+/− SEM)