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. 2014 Jul 25;10(5):645–653. doi: 10.1093/scan/nsu099

Table 1.

Regions that show significant differences in activation between mothers with IPV-PTSD and HC when watching scenes depicting menace and prosocial scenes combined (emotional scenes) contrasted with neutral scenes

Cluster size xyz Region This cluster also includes Mean menace vs neutral Mean prosocial vs neutral Main effect group Main effect film condition Group × film-condition interaction Tukey test on significant interactions R-value of the correlation of PTSD symptom severity and activation within IPV-PTSD group

  • PTSD

  • (s.d.)

  • controls

  • (s.d.)

  • PTSD

  • (s.d.)

  • controls

  • (s.d.)

 F(1, 33) P F(1, 33) P F(1, 33) P P values; only values <0.05 given P value
Main effect group Emotion vs neutral contrast
IPV-PTSD > controls
28 30 −10 −17 Right Hippocampus

  • 0.246 (0.25)

  • 0.059 (0.12)

  • 0.226 (0.21)

  • 0.031 (0.14)

 12.499 .001 0.612 0.440 0.018 0.895

  • 0.006C

  • 0.014E

  • 0.020B

  • 0.046D

  • 0.188

  • 0.503
Controls > IPV-PTSD
51 −15 41 −14 Left vmPFC ACC

  • −0.150 (0.12)

  • −0.005 (0.15)

  • −0.096 (0.19)

  • 0.039 (0.14)

 15.549 <0.001 1.781 0.191 0.015 0.905

  • 0.003C

  • 0.033B

  • −0.300

  • 0.277
338 −33 −34 58 Left postcentral gyrus Left SPL

  • −0.133 (0.19)

  • 0.102 (0.24)

  • −0.162 (0.29)

  • 0.128 (0.15)

 15.948 <0.001 0.003 0.960 0.509 0.481

  • 0.002E

  • 0.005D

  • 0.006C

  • 0.016B

  • 0.293

  • 0.290
33 42 −49 46 Right IPL

  • −0.468 (0.24)

  • 0.108 (0.23)

  • −0.071 (0.17)

  • 0.200 (0.22)

 13.433 0.001 0.522 0.475 1.510 0.228

  • 0.003E

  • 0.008C

  • 0.123

  • 0.663
30 −60 −16 40 Left precentral gyrus

  • −0.154 (0.32)

  • 0.418 (0.19)

  • −0.128 (0.20)

  • 0.098 (0.15)

 12.737 0.001 0.847 0.364 0.117 0.734

  • 0.006C

  • 0.017E

  • 0.049B

  • −0.524

  • 0.045
105 30 −37 −29 Right cerebellum anterior lobe

  • 0.084 (0.21)

  • 0.259 (0.21)

  • −0.187 (0.25)

  • 0.135 (0.20)

 19.475 <0.001 17.725 <0.001 2.466 0.126

  • <0.001D

  • <0.001E

  • 0.002A

  • −0.463

  • 0.082
Interaction group × film condition Menacing vs prosocial contrast
709 36 50 16 Right dlPFC

  • dmPFC

  • Left dlPFC

  • (ACC)

  • 0.113 (0.23)

  • −0.045 (0.20)

  • −0.149 (0.22)

  • 0.048 (0.19)

 0.101 0.752 5.913 0.021 26.348 <0.001

  • 0.002A

  • 0.036E

  • −0.430

  • 0.110
33 36 26 43 Right dlPFC

  • 0.026 (0.12)

  • −0.008 (0.19)

  • −0.142 (0.15)

  • 0.047 (0.13)

 3.313 0.078 4.245 0.047 16.745 <0.001

  • 0.001A

  • 0.002E

  • −0.152

  • 0.589
99 −18 26 55 Left dlPFC

  • 0.020 (0.14)

  • −0.110 (0.17)

  • −0.113 (0.23)

  • 0.024 (0.14)

 0.005 0.943 0.000 0.994 16.378 <0.001

  • 0.046A

  • 0.025F

  • 0.292

  • 0.290
33 39 −31 19 Right insula (operculum)

  • 0.098 (0.14)

  • −0.019 (0.10)

  • −0.019 (0.20)

  • 0.083 (0.12)

 0.037 0.848 0.064 0.802 14.20 0.001 0.047A

  • −0.285

  • 0.303
32 −54 11 34 Left precentral gyrus

  • 0.225 (0.35)

  • 0.079 (0.17)

  • −0.073 (0.38)

  • 0.123 (0.22)

 0.074 0.788 12.830 0.001 23.082 <0.001 <0.001A

  • −0.260

  • 0.349
48 48 −58 52 Right IPL

  • −0.180 (0.27)

  • −0.285 (0.32)

  • −0.237 (0.35)

  • 0.096 (0.20)

 2.079 0.159 7.752 0.009 14.188 0.001

  • <0.001F

  • 0.006E

  • 0.033C

  • −0.360

  • 0.187
66 3 −58 −5 Right cerebellum anterior lobe

  • 0.134 (0.24)

  • 0.016 (0.25)

  • −0.210 (0.35)

  • 0.082 (0.35)

 1.017 0.321 6.411 0.016 13.806 0.001

  • 0.001A

  • 0.031E

  • 0.180

  • 0.520
Main effect film condition
Menacing > prosocial
501 −9 50 28 dmPFC

  • Left dlPFC

  • Right dlPFC

  • (dACC)

  • 0.063 (0.17)

  • 0.088 (0.17)

  • -−0.137 (0.21)

  • 0.032 (0.13)

 3.235 0.081 37.042 <0.001 11.540 0.002

  • <0.001A

  • 0.002D

  • 0.028E
1744 27 8 55 Right dlPFC

  • Right OFC,

  • Right precentral Gyrus

  • 0.202 (0.22)

  • 0.245 (0.26)

  • −0.043 (0.26)

  • 0.031 (0.17)

 0.731 0.399 50.565 <0.001 0.188 0.668

  • <0.001A

  • <0.001F

  • 0.003D
32 3 17 22 dACC

  • 0.090 (0.18)

  • 0.058 (0.20)

  • −0.065 (0.22)

  • −0.037 (0.15)

 0.001 0.972 21.858 <0.001 1.253 0.271 0.002A
573 −51 35 −2 Left OFC Left precentral gyrus

  • 0.196 (0.28)

  • 0.137 (0.22)

  • −0.015 (0.31)

  • −0.028 (0.18)

 0.218 0.644 31.856 <0.001 0.471 0.497

  • <0.001A

  • 0.005F
16099 42 −76 19 Right Occipital lobe

  • Left Occipital lobe, cerebellum, bilateral precuneus,

  • thalamus, bilateral temporal lobe, PCC

  • 0.633 (0.24)

  • 0.659 (0.17)

  • 0.022 (0.19)

  • 0.080 (0.18)

 0.497 0.486 376.080 <0.001 0.269 0.608

  • <0.001A

  • <0.001C

  • <0.001D

  • <0.001F
667 −21 8 64 Left Superior frontal gyrus

  • Left precentral gyrus

  • L SMA

  • 0.262 (0.17)

  • 0.125 (0.19)

  • −0.064 (0.25)

  • −0.060 (0.25)

 1.028 0.318 42.579 <0.001 3.257 0.080

  • <0.001A

  • <0.001C

  • 0.007F
Prosocial > menacing
176 −36 −22 19 Left insula Left rolandic operculum

  • −0.185 0.23)

  • −0.131 (0.15)

  • −0.108 (0.26)

  • 0.047 (0.15)

 3.175 0.084 14.787 0.001 2.292 0.140

  • 0.002F

  • 0.006C
45 39 −19 19 Right insula Right rolandic operculum

  • −0.153 (0.22)

  • −0.105 (0.18)

  • −0.086 (0.23)

  • 0.074 (0.16)

 3.058 0.090 14.778 0.001 3.088 0.88

  • 0.001F

  • 0.008C
82 9 −7 28 (mid) cingulate Limbic lobe

  • 0.069 (0.22)

  • −0.080 (0.15)

  • 0.174 (0.27)

  • 0.082 (0.22)

 3.561 0.068 12.947 0.001 0.596 0.446

  • 0.006D

  • 0.014F
254 −6 −22 64 Paracentral lobule

  • Right SMA

  • R precentral gyrus

  • −0.187 (0.24)

  • −0.124 (0.15)

  • −0.087 (0.19)

  • 0.079 (0.15)

 4.811 0.035 22.128 <0.001 2.549 0.120

  • <0.001A

  • <0.001F

  • 0.044C
38 51 −28 1 Right STG

  • 0.019 (0.19)

  • −0.046 (0.20)

  • 0.105 (0.15)

  • 0.095 (0.13)

 0.586 0.450 13.795 0.001 0.814 0.373 0.009F
32 −45 −70 46 Left angular gyrus

  • −0.125 (0.19)

  • −0.411 (0.29)

  • −0.084 (0.25)

  • −0.022 (0.18)

 3.296 0.079 17.902 <0.001 11.727 0.002

  • <0.001D

  • <0.001F

  • 0.004A
40 45 −64 49 Right angular gyrus

  • −0.22 (0.25)

  • -−0.186 (0.30)

  • −0.186 (0.30)

  • 0.031 (0.29)

 0.063 0.804 15.896 <0.001 11.328 0.002 <0.001F
36 60 −1 7 Right precenral gyrus

  • −0.112 (0.32)

  • −0.116 (0.27)

  • −0.037 (0.35)

  • 0.090 (0.26)

 0.466 0.500 9.878 0.004 2.136 0.153 0.009F

Legend for interaction tests: A = IPV-PTSD menacing-neutral vs IPV-PTSD prosocial-neutral; B = IPV-PTSD menacing-neutral vs HC menacing-neutral; C = IPV-PTSD menacing-neutral vs HC prosocial-neutral; D = IPV-PTSD prosocial-neutral vs HC menacing-neutral; E = IPV-PTSD prosocial-neutral vs HC menacing-neutral; F = HC menacing-neutral vs HC prosocial-neutral. Abbreviations: ACC = Anterior Cingulate Cortex; dACC dorsal Anterior Cingulate Cortex; dlPFC = dorsolateral Prefrontal Cortex; dmPFC = dorsomedial Prefrontal Cortex; IPL = Inferior Parietal Lobule; OFC = Orbitofrontal Cortex; PCC = Posterior Cingulate Cortex; SMA = Supplementary Motor Area; STG = Superior Temporal Gyrus; vmPFC = ventromedial Prefrontal Cortex.