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. 2015 Jan 7;35(4):554–564. doi: 10.1038/jcbfm.2014.231

Figure 4.

Figure 4

Effects of running and cafeteria-diet on brain metabolite concentrations in the prefrontal cortex (PFC) (institutional units, i.U.). For metabolites in the PFC, MANOVA yielded no significance for the factor running (P=0.967) but a highly significant effect for cafeteria diet (P<0.001) with a significant effect on glutamate (Glu) (P=0.01). In post hoc analyses, CR (11.3±0.6 i.U.) mice showed lower Glu levels than SR (12.3±0.7 i.U.) mice (P=0.027) (A). As in the hippocampal voxel, there was only a trend seen in terms of higher glucose levels for cafeteria diet (F(1,24)=3.5, P=0.054) in an univariate ANOVA, which would also not survive the first multiple comparison (B). The Lac level was not significantly influenced neither by running nor by diet. CR, cafeteria running; CS, cafeteria sedentary; SR, standard running; SS, standard sedentary.