Survival curve of wild-type (WT, n = 11) and uncoupling protein-3-deficient (Ucp3−/−) mice (n = 12) after ip injection of fecal slurry. Sham mice (10 WT, 9 Ucp3−/−) received ip saline. All animals received sc fluids at 0-, 6-, 18-, 30-, and 42-h time points. KO, knockout.