FIG 2.

(A) Homology model of full-length TP_0326 BamA based on the crystal structure of Neisseria gonorrhoeae BamA (12) showing the 16-stranded β-barrel and the five-domain periplasmic POTRA arm (P1 to P5). The three large predicted extracellular loops L4, L6, and L7 are shown in red, blue, and magenta, respectively. (B) Enlargement of β-barrel domain depicted as a ribbon model. The lateral opening and exit pore in the homology model are outlined by the dashed oval. (C) Predicted two-dimensional topology of the TP_0326 β-barrel. The amino acids predicted to demarcate the extracellular and periplasmic boundaries of each β strand are indicated. The polyserine tract in L7 is indicated by S's. (D) Side and top views of the β-barrel. Surface representations of L3, L4, L6, and L7 are shown using the same colors as in panels A and C. The polyserine tract in L7 is indicated with spikes.