Table 2.
VBM/VBCT volume decreases (e.g., atrophy) at whole brain before training between patients and healthy controls.
| Region | Z score | P value (cluster, FWE-corrected) | Cluster extent (voxel) | MNI coordinates | ||
|---|---|---|---|---|---|---|
| x (mm) | y (mm) | z (mm) | ||||
| VBM | ||||||
| Brainstem (medulla oblongata) | 4.88 | <0.001 | 300 | −6 | −48 | −61 |
| Cerebellum (lobule IX) | 3.95 | <0.001 | 353 | −6 | −51 | −31 |
| VBCT | ||||||
| Primary motor cortex* | 3.63 | <0.001 | 46 | −23 | −30 | 59 |
*Analysis was performed in the sensorimotor cortex to increase sensitivity (Freund et al., 2011). VBM = voxel-based morphometry; VBCT = voxel-based cortical thickness.