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. 2015 Apr 29;5(4):e007702. doi: 10.1136/bmjopen-2015-007702

Table 3.

Survival in patients with BC with bone metastases (N=2427) by stage of disease at BC diagnosis and by length of bone metastasis-free interval

1-year survival % (95% CI) 3-year survival* % (95% CI) 5-year survival† % (95% CI)
Stage of disease at BC diagnosis
 Localised 59.0 (54.2 to 63.6) 35.2 (30.2 to 40.2) 19.6 (15.3 to 24.5)
 Regional 50.7 (47.9 to 53.5) 25.0 (22.4 to 27.7) 12.4 (10.2 to 14.9)
 Metastatic 52.0 (47.9 to 55.9) 22.8 (19.3 to 26.6) 9.5 (6.9 to 12.6)
 Unknown 49.7 (42.6 to 56.5) 27.3 (20.2 to 34.9) 13.3 (7.3 to 21.2)
Length of bone metastasis-free interval (years)
 <1 64.4 (61.2 to 67.4) 37.8 (34.4 to 41.2) 21.0 (17.9 to 24.2)
 1 to <3 39.9 (36.3 to 43.6) 16.4 (13.5 to 19.5) 6.7 (4.7 to 9.2)
 3 to <5 47.0 (42.4 to 51.4) 18.5 (14.7 to 22.6) 7.4 (4.7 to 10.9)
 ≥5 52.6 (47.4 to 57.6) 25.7 (20.5 to 31.3) 8.6 (4.8 to 13.7)
 Overall 52.4 (50.4 to 54.4) 26.4 (24.5 to 28.3) 13.1 (11.4 to 14.8)

*Restricted to patients with bone metastasis diagnosed prior to 2010.

†Restricted to patients with bone metastasis diagnosed prior to 2008.

BC, breast cancer.