Table 2.
Serum lipid levels in a rat model of menopausal hyperlipidemia.
| Sham | OVX-Con | OVX-SV | OVX-SGJT (50) | OVX-SGJT (150) | OVX-SGJT (450) | |
|---|---|---|---|---|---|---|
| (n = 5) | (n = 5) | (n = 5) | (n = 5) | (n = 5) | (n = 5) | |
| T-CHO (mg/dL) | 113.50 ± 2.179 | 221.25 ± 6.142a∗∗ | 178.50 ± 35.624bc | 147.00 ± 3.894c | 178.75 ± 0.081bc | 195.75 ± 18.6221ab |
| TG (mg/dL) | 46.6 ± 7.80 | 64.06 ± 6.06a∗ | 48.33 ± 3.21a | 46.25 ± 4.66a | 60.00 ± 4.38a | 56.75 ± 10.56a |
| HDL (mg/dL) | 67.2 ± 4.03 | 31.8 ± 4.5a∗∗ | 41.6 ± 3.14b | 36.00 ± 2.71ab | 41.8 ± 8.31b | 44.00 ± 3.86b |
| LDL (mg/dL) | 37.52 ± 3.83 | 176.64 ± 0.43a∗∗ | 127.23 ± 31.842bc | 101.89 ± 3.879c | 125.08 ± 17.947bc | 151.75 ± 15.823ab |
Sham, Sham rats fed a high-fat (HFD), high-cholesterol diet (HCD); OVX-Con, OVX rats fed a high-fat (HFD), high-cholesterol diet (HCD); OVX-SV, OVX rats fed a high-fat (HFD), high-cholesterol diet (HCD) supplemented with simvastatin (20 mg/kg); OVX-SGJT, OVX rats fed a high-fat (HFD), high-cholesterol diet (HCD) supplemented with SGJT (50, 150, 450 mg/kg). After 8 weeks, the serum levels of TC, TG, HDL, and LDL were measured. Values are expressed as means ± SD (n = 5). ∗Significantly different between the sham and OVX-Con at P < 0.01, ∗∗ P < 0.001 (two-sample t-test). Values not sharing a common alphabet as superscripts are significantly different from each other at the level of P < 0.05 (ANOVA followed by Duncan's test).