Effect of PRMSE on expression of virulence genes for E. coli CFT073 (A), P. mirabilis HI4320 (B), P. aeruginosa PAO1 (C), and P. aeruginosa PA14 (D). Error bars show the standard deviations of values obtained from three replications. All cases of gene expression were normalized to levels for the corresponding housekeeping gene (gapA of E. coli CFT073, rpoA of P. mirabilis HI4320, and rpoD of P. aeruginosa PAO1 and PA14) and then were related to the normalized expression level of the same gene in the control. An asterisk indicates a statistically significant difference in measured values compared to the control (P < 0.05 by Student's t test).