TABLE 3.
Interaction of phenolic constituents of PRMSE with ciprofloxacin
| Bacterial strain and constituent | Value for measure of interaction |
|||
|---|---|---|---|---|
| MIC (mg ml−1) | FIC of ciprofloxacin | FIC of compound | FICI | |
| E. coli CFT073 | ||||
| Gallic acid | 5 | 1 | 1 | 2 |
| Catechol | 1.25 | 0.25 | 0.25 | 0.5a |
| Catechaldehyde | 1.25 | 1 | 1 | 2 |
| Syringaldehyde | 5 | 0.5 | 0.25 | 0.75 |
| P. mirabilis HI4320 | ||||
| Gallic acid | 5 | 1 | 1 | 2 |
| Catechol | 1.25 | 0.25 | 0.25 | 0.5a |
| Catechaldehyde | 1.25 | 0.5 | 1 | 1.5 |
| Syringaldehyde | 5 | 0.5 | 0.5 | 1 |
| P. aeruginosa PAO1 | ||||
| Gallic acid | 5 | 1 | 1 | 2 |
| Catechol | 2.5 | 0.25 | 0.25 | 0.5a |
| Catechaldehyde | 1.25 | 0.5 | 0.51 | 1.01 |
| Syringaldehyde | 5 | 1 | 1 | 2 |
| P. aeruginosa PA14 | ||||
| Gallic acid | 5 | 1 | 1 | 2 |
| Catechol | 2.5 | 0.25 | 0.25 | 0.5a |
| Catechaldehyde | 1.25 | 1 | 1 | 2 |
| Syringaldehyde | 5 | 0.5 | 0.25 | 0.75 |
a
Values represent synergistic interaction.