Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The regulation and action of FGF23 without the functioning kidney. FGF23 production in the bone is continuously stimulated by phosphate load, calcitriol (analogue) treatment and possibly by high PTH. It remains to be elucidated whether very high FGF23 in dialysis patients would inhibit PTH expression by activating its cognate FGFRs in a Klotho-dependent fashion.
