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Correspondence between the simplified restriction map of the URA2 locus and protein domains. The thick line indicates the URA2 coding sequence (restriction site: b, BglII; B, BamHI). A, C, D, B, and E denote the BamHI-BglII subfragments, ns15 and ns30 the positions of the nonsense mutations, and fs72 the position of the frameshift mutation (GATase, glutamine amidotransferase; CPSase, carbamoylphosphate synthetase; DHOase-like, dihydroorotase-like; ATCase, aspartate transcarbamylase).
