Table 1.
Summary of the vasomotor responses of isolated trout coronary microvessels to increasing concentrations of several vasoactive agents
| Vasoactive Agent | N | Dose Dependency | Temperature Effect | Acclimation Temperature, °C | Resting ID, μm | Maximal ID, μm | Maximal Change from Resting ID, % |
|---|---|---|---|---|---|---|---|
| EPI | 8 | Constriction/Dilation | Yes; weaker at 1°C | 1 | 78.8 | 110.9 | 12 (+) |
| 5 | 66.0 | 90.7 | 28 (+) | ||||
| 10 | 83.1 | 139.6 | 34 (+) | ||||
| NE | 8 | Constriction/Dilation | No | 1 | 74.3 | 102.2 | 19 (+) |
| 5 | 65.0 | 94.1 | 27 (+) | ||||
| 10 | 94.2 | 145.5 | 32 (+) | ||||
| ADE | 8 (1°C & 5°C)/10 (10°C) | Dilation | Yes; weaker at 5°C and 1°C | 1 | 70.3 | 108.1 | 52 (+) |
| 5 | 84.9 | 117.8 | 42 (+) | ||||
| 10 | 86.8 | 140.4 | 61 (+) | ||||
| SER | 8 | Constriction/Dilation | Yes; weaker at 5°C and 1°C | 1 | 77.4 | 110.9 | 12 (+) |
| 5 | 91.3 | 125.8 | 13 (+) | ||||
| 10 | 87.9 | 126.2 | 27 (+) | ||||
| ACh | 8 | Constriction | Yes; stronger at 5°C and 1°C | 1 | 75.8 | 110.9 | 14 (−) |
| 5 | 60.5 | 96.3 | 18 (−) | ||||
| 10 | 78.8 | 142.4 | 7 (−) | ||||
| BK | 8 | Constriction/Dilation | Yes; variable | 1 | 74.9 | 105.1 | 9 (+) |
| 5 | 64.4 | 106.3 | 10 (−) | ||||
| 10 | 85.8 | 118.7 | 12 (−)/6 (+) | ||||
| ET-1 | 8 | Constriction | Yes; more sensitive at 1°C | 1 | 85.4 | 102.2 | 81 (−) |
| 5 | 67.7 | 102.0 | 84 (−) | ||||
| 10 | 85.4 | 119.8 | 79 (−) | ||||
| SNP | 8 | Constriction/Dilation | Yes; variable | 1 | 80.7 | 102.2 | 8 (+) |
| 5 | 66.8 | 84.1 | 8 (−) | ||||
| 10 | 83.7 | 130.7 | 35 (+) |
Values represent the vasomotor responses of isolated trout coronary microvessels to increasing concentrations of several vasoactive agents at 3 acclimation/test temperatures (1°C, 5°C, and 10°C). EPI, epinephrine; NE, norepinephrine; ADE, adenosine; SER, serotonin; ACh, acetylcholine; BK, bradykinin; ET-1, Endothelin-1; SNP, sodium nitroprusside. The average resting and maximal internal diameter (ID), the general response(s) of the vessels to increasing agent concentration and acclimation temperature, and the maximal change from resting ID [dilation (+), constriction (−)] are shown for each agent.