Fig. 3.
Experimental recordings of the cardiorespiratory responses to bolus injection of capsaicin (CAP, 0.5 μg/kg iv) into the right atrium in anesthetized and spontaneously breathing rat pups. A: ventilatory responses to CAP in a Ctrl (left) and a PNE pup (right). In each panel, the traces from the top to bottom are tidal volume (VT), respiratory frequency (fR), minute ventilation (VE), and event markers (arrows) for CAP injection. B–D: group data showing the responses of expiratory duration tE (apnea), heart rate (HR), and mean arterial blood pressure (MABP) to CAP; n = 9 and 10 for Ctrl and PNE pups; means ± SE; *P < 0.01 compared with baseline (as 0) and †P < 0.01 between Ctrl and PNE pups.