Fig. 6.

Expression profile for Sry and Sox3 in the rat using data from the Rat BodyMap project. Expression profile for Sox3 (gray) and Sry (black) in female (F) and male (M) RNA-Seq data for 10 tissues in the Fisher 344 rat (A). Each tissue is a pool of 16 individual RNA-Seq experiments (4 animals at 4 ages). Data are shown as reads per kilobase per million (RPKM). While Sry is ubiquitously expressed in male only, Sox3 transcripts are found at all 4 ages (2, 6 21, and 104 wk old rats) in the male testis (B) and brain (C). The kidney showed expression of Sry at all 4 ages with no detectable Sox3 reads (D). Error bars for the individual tissues (B–D) represent the SE of 4 independent RNA-Seq datasets at each age. E: analysis of primate (Homo sapiens, Gorilla gorilla, Macaca mulatta, Pan troglodytes) kidney and testis SRA datasets for expression of SOX3 (gray) or SRY (black). Expression of both SRY and SOX3 are seen in testis, while only SRY expression is found in kidney.