Table 1.
Lipid Profiles in Tail and Peritoneal Macrophages from Wild-Type (WT) and fat-1 Mice
Mean mol per 100 mol total fatty acids ± SEM |
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---|---|---|---|---|
Tail Snip |
Peritoneal Macrophages |
|||
Fatty acid | WT | fat-1 | WT | fat-1 |
18:2n-6 | 17.43 ± 0.8 | 15.87 ± 0.9 | 7.4 ± 0.4 | 10.26 ± 0.4 |
18:3n-3 | 0.05 ± 0.1 | 1.70 ± 0.1a | 1.94 ± 0.1 | 2.12 ± 0.2 |
20:4n-6 | 5.16 ± 0.3 | 0.57 ± 0.2a | 17.66 ± 1.2 | 14.31 ± 1.2 |
20:5n-3 | 0.05 ± 0.1 | 1.93 ± 0.2a | 0 ± 0 | 1.68 ± 0.6a |
22:4n-6 | 2.46 ± 0.2 | 0.32 ± 0.3a | 4.27 ± 0.2 | 0.99 ± 0.2a |
22:5n-6 | 3.32 ± 0.2 | 0.06 ± 0.1a | 3.00 ± 0.2 | 0.58 ± 0.3a |
22:5n-3 | 0.05 ± 0.02 | 3.04 ± 0.21a | 0 ± 0 | 1.89 ± 0.47a |
22:6n-3 | 0.01 ± 0.01 | 3.29 ± 0.26a | 0 ± 0 | 1.52 ± 0.17a |
n:6/n-3 ratio | 28.24 ± 0.91 | 1.81 ± 0.15a | 24.93 ± 1.65 | 4.25 ± 2.05 |
NOTE. Total lipids were extracted and analyzed by gas chromatography, as described in the Materials and Methods. Only selected major fatty acids (>1 mol %) are reported. SEM, standard error of the mean.
P<.05.