Table 1.
Demographic, Baseline, and Cue-Exposure Session Characteristics by Medication Group
| Demographic characteristics | Placebo
|
Divalproex
|
Total
|
|||
|---|---|---|---|---|---|---|
| n | % | n | % | n | % | |
| Gender | ||||||
| Male | 17 | 23.6 | 12 | 16.7 | 29 | 40.3 |
| Female | 19 | 26.4 | 24 | 33.3 | 43 | 59.7 |
| Total | 36 | 50.0 | 36 | 50.0 | 72 | 100.0 |
| Race/ethnicity | ||||||
| White | 30 | 41.7 | 32 | 44.8 | 62 | 86.1 |
| African American | 5 | 6.9 | 4 | 5.6 | 9 | 12.5 |
| Other | 1 | 1.4 | 0 | 0.0 | 1 | 1.4 |
| Total | 36 | 50.0 | 36 | 50.0 | 72 | 100.0 |
|
M
|
SD
|
M
|
SD
|
M
|
SD
|
|
| Age | 43.42 | 12.19 | 43.51 | 9.71 | 43.46 | 10.96 |
| Years of formal education | 14.78 | 2.37 | 14.72 | 1.92 | 14.75 | 2.14 |
| No. of previous quit attempts | 3.33 | 3.32 | 4.06 | 2.81 | 3.69 | 3.08 |
| Cigarettes smoked per day | 25.40 | 9.65 | 24.14 | 7.19 | 24.76 | 8.46 |
| Baseline session | ||||||
| Nicotine dependence score (FTQ) | 6.56 | 1.83 | 6.83 | 1.87 | 6.69 | 1.84 |
| Expired carbon monoxide | 29.72 | 10.60 | 28.69 | 14.16 | 29.21 | 12.43 |
| QSU–Brief total | 34.67 | 10.76 | 30.61 | 14.03 | 32.64 | 12.58 |
| SCL–90 Global Severity | 0.15 | 0.17 | 0.18 | 0.19 | 0.17 | 0.18 |
| SCL–90 Positive Symptom Distress | 1.00 | 0.45 | 1.05 | 0.30 | 1.03 | 0.38 |
| SCL–90 Positive Symptom total | 11.23 | 11.14 | 13.56 | 12.91 | 12.41 | 12.04 |
| Cue reactivity session | ||||||
| Days since baseline session | 26.83 | 14.24 | 26.03 | 12.86 | 26.43 | 13.48 |
| Hours since last cigarette | 33.74 | 59.66 | 14.07 | 24.0 | 23.90 | 46.21 |
| Expired carbon monoxide | 11.00 | 9.76 | 11.59 | 7.68 | 11.29 | 8.75 |
| QSU–Brief total | 29.74 | 12.22 | 32.97 | 12.30 | 31.33 | 12.28 |
| Mood Form (Negative Affect scale) | 4.09 | 4.62 | 4.88 | 5.62 | 4.48 | 5.12 |
| Mood Form (Positive Affect scale) | 12.19 | 5.22 | 12.65 | 5.40 | 12.41 | 5.27 |
| Dosing and compliance | ||||||
| No. 250 mg pills prescribed per week | 45.5 | 13.54 | 41.2 | 10.15 | 43.48 | 12.10 |
| % compliance/pre cue Rx | 0.94 | 0.11 | 0.91 | 0.14 | 0.92 | 0.13 |
| % compliance week of cue Rx | 0.90 | 0.16 | 0.90 | 0.20 | 0.90 | 0.18 |
| % compliance/total | 0.93 | 0.13 | 0.90 | 0.14 | 0.92 | 0.13 |
Note. There were no significant medication group differences for any of the variables listed above (all ps > .05). FTQ = Fagerström Tolerance Questionnaire; QSU–B = Questionnaire on Smoking Urges–Brief; SCL–90 = Symptom Checklist–90.