Table I. Rare copy number variants (CNVs): risks of illness for autism spectrum disorder (ASD), schizophrenia (SCZ) and bipolar disorder (BD).47 Risks of illness are based on Bayesian probabilities. Data from Malhotra and Sebat's 2012 review.21.
From ref 47: Gershon ES, Alliey-Rodriguez N. New ethical issues for genetic coun seling in common mental disorders. Am J Psychiatry. 2013;170:968-976. Copyright © American Psychiatric Association 2013.
| CNV Locus | Type | ASD | SZ | BD | Risk of any of these disorders |
| 1q21.1 | Deletion | 7.91% | 7.91% | ||
| Duplication | 4.97% | 4.50% | 9.25% | ||
| 3q29 | Deletion | 33.56% | 33.56% | ||
| 7q11.23 | Duplication | 16.05% | 16.05% | ||
| 15q11.2 | Deletion | 2.09% | 2.09% | ||
| 15q11.2-13.1 | Duplication | 20.73% | 20.73% | ||
| 15q13.3 | Deletion | 5.42% | 8.76% | 13.70% | |
| 16p11.2 | Deletion | 5.96% | 5.96% | ||
| Duplication | 7.28% | 9.45% | 4.19% | 19.56% | |
| 17p12 | Deletion | 6.60% | 6.60% | ||
| 22q11.21 | Deletion | 23.06% | 68.25% | 26.37% | 82.01% |
| 22q11.2 | Duplication | 2.07% | 2.07% |