Table 1.
Sample Characteristics1
| Baseline Variables2 | |
| Age (years)3 | Median 41 (IQR: 36, 47) |
| Duration of known HIV status at time of enrollment (years)4 | Median 9.2 (IQR: 4.0, 16.1) |
| HIV RNA level (copies/ml) | Median 336.5 (IQR: 50, 2600) |
| CD4+ T cell count (cells/µl) | Median 295 (IQR: 143, 444) |
| Male5 | N=855 (64.7%) |
| Man who has sex with men6 | N=499 (42.7%) |
| Injection drug use before HIV diagnosis7 | N=186 (19.3%) |
| ART Naïve at time of enrollment8 | N=217 (16.9%) |
| Time-varying Variables9 | |
| HIV RNA level>1000 copies/ml | N=607 (19.6%) |
| Most recent CD4+ T cell count (cells/µl) | Median 338 (IQR: 176, 500) |
| Time since most recent CD4+ T cell count (days) | Median 142 (IQR: 79, 274) |
| Time since most recent HIV RNA (days) | Median 45 (IQR: 28, 99) |
| Days monitored using MEMS in previous 3 months | Median 78 (IQR: 28, 91) |
| Percent doses taken (%) in previous 3 months | Median 84 (IQR: 50, 98) |
| Number of interruptions >= 24 hours in previous 3 months | Median 4 (IQR: 1, 11) |
| Number of interruptions >= 72 hours in previous 3 months | Median 0 (IQR: 0, 1) |
| NNRTI Regimen | N=806 (26.0%) |
| Non-boosted PI Regimen | N=553 (17.9%) |
| Boosted PI Regimen | N=901 (29.1%) |
| Other10 | N=836 (27%) |
1
For analysis of failure=HIV RNA>1000 copies/ml; results for failure=HIV RNA>400 copies/ml differ slightly due to censoring at first failure.
2
Among 1478 patients meeting inclusion criteria
3
55 (10.5%) missing age
4
166 (11.2%) missing duration of known HIV status
5
157 (10.6%) missing sex
6
310 (21.0%) missing whether a man who has sex with men
7
510 (34.6%) missing injection drug use
8
192 (13.0%) missing whether ART naive at time of enrollment
9
Summarized over 3096 postbaseline HIV RNA tests meeting inclusion criteria.
10
Included regimens with two nucleoside reverse transcriptase inhibitors but no other reported drug, regimens based on fusion inhibitors, and unspecified/unknown regimens.