Table 2.

Comparison of baseline and 6-month post supplementation characteristics in both groups.

Characteristics	Group A (n=15)			Group B (n=17)			P †	P ‡	Mean (CI) difference in change between groups
At baseline	At 6 months	P*	At baseline	At 6 months	P*
BMI (Kg/m2)	26.8±4.57	25.4±5.65	0.1	26.8±6.12	25.9±6.05	0.05	0.97	0.47	0.56 (−1.0, 2.14)
Serum testosterone (ng/ml)	0.47±0.19	0.35±0.12	0.03	0.55±0.18	0.52±0.11	0.51	0.19	0.17	0.08(−0.42, 0.21)
Serum DHEAS (μg/dl)	236.5±85.57	238.3±126	0.93	269.1±100.7	305±98.36	0.38	0.33	0.5	26.8 (−53.6, 07)
Serum calcium (mg/dl)	9.7±0.43	9.4±0.47	0.09	9.3±0.61	9.3±0.55	0.71	0.08	0.34	0.22 (−0.26, 0.7)
Serum phosphate (mg/dl)	3.7±0.57	3.8±0.63	0.2	3.3±0.74	3.5±0.53	0.06	0.12	0.71	0.06 (−0.2, 0.43)
Serum alkaline phosphatase (IU/l)	276±70	247±46	0.15	258±136	247±90	0.56	0.29	0.49	18.2 (−35.8, 72.2)
Serum albumin (mg/dl)	4.9±0.24	4.9±0.42	0.65	4.8±0.16	4.8±0.35	0.72	0.18	0.84	−0.03 (−0.33, 0.2)
Serum total cholesterol (mg/dl)	172±31	158±20	0.08	169±31	154±27	0.001	0.76	0.91	−0.9 (−16.9, 15.1)
Serum LDL cholesterol (mg/dl)	107±16	102±13	0.28	108±29	102±27	0.30	0.96	0.93	−0.62 (−16.1, 14.9)
Serum triglyceride (mg/dl)	116±102	81±42	<0.01	91±35	80±30	0.02	0.38	0.22	24.22 (−10.9, 59.4)
Serum HDL cholesterol (mg/dl)	42±3	43±6	0.36	40±6	42±6	0.30	0.27	0.91	0.23 (−4.3, 4.77)
Urinary calcium:creatinine ratio	0.10±0.05	0.11±0.06	0.31	0.10±0.06	0.09±0.06	0.57	0.91	0.25	−0.027 (−0.07, 0.02)
Serum intact PTH (pg/ml)	59.2±22.51	42.6±15.96	0.0008	53.5±23.65	52.7±18.58	0.83	0.49	0.007	15.84 (4.6, 27.02)
Serum 25 (OH) vitamin D (ng/ml)	7.7±6.05	31.5±13.88	<0.001	6.8±2.46	6.7±2.31	0.94	0.96	<0.001	−23.8 (−30, −16.9)
Fasting plasma glucose (mg/dl)	87.9±7.22	90±7	0.43	87.6±12.97	89±8	0.65	0.95	0.92	−0.5 (−10.9, 9.8)
Fasting plasma insulin (μU/ml)	17.3±15.28	10.3±5.92	<0.01	14.0±10.90	12.2±6.67	0.18	0.36	0.10	5.18 (−1.02, 11.39)
HOMA-IR	3.8±3.40	2.3±1.32	0.03	3.1±2.30	2.6±1.32	0.32	0.36	0.16	1.05 (−0.45, 2.56)
AUC–glucose	231.9±46.44	240.9±41.0	0.60	239.3±35.77	246.6±35.8	0.53	0.50	0.93	−1.72 (−42.6, 39.2)
AUC–insulin	191.0±142.91	138.5±54.55	0.12	187.9±106.77	181.4±151.00	0.76	0.49	0.64	46.0 (−29.8, 121.8)
Matsuda index	3.7±2.41	4.3±2.02	0.31	4.3±2.92	4.3±2.89	0.98	0.62	0.51	−0.64 (−2.67, 1.38)
Insulinogenic index	2.2±1.29	1.9±1.66	0.44	2.6±3.19	1.8±1.53	0.33	0.65	0.30	−0.52 (−2.41, 1.36)
Disposition index	7.7±5.48	8.1±7.79	0.86	8.4±10.08	6.0±3.93	0.79	0.99	0.95	−2.9 (−10.39, 4.63)
AoPWV (m/s)	5.6±1.30	6.2±1.32	0.22	6.5±1.25	6.3±1.04	0.61	0.08	0.16	−0.70 (−1.70, 0.31)
Augmentation index	11.9±10.72	10.6±10.50	0.89	12.1±7.73	11.4	0.94	0.98	0.78	1.23 (−7.84, 10.3)

*P, difference between baseline and 6 months; ^† P, difference between the two groups at baseline; ^‡ P, difference between two groups at the end of 6 months; AUC, area under the curve; AoPWV, aortic pulse wave velocity.