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. 2015 Apr 21;11:20. doi: 10.1186/s12990-015-0021-6

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© Yamanaka et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Changes in membrane potential produced by TRPA1 activation in SG neurons. (A) A continuous current-clamp recording of the membrane potential showing that AITC (300 μM) evokes hyperpolarization. (B) A continuous current-clamp recording of the membrane potential showing that AITC (300 μM) evokes depolarization in the presence of TTX. (C) Membrane potential of SG neurons under the action of AITC (n = 5) relative to control (left). Membrane potential of SG neurons under the action of AITC in the presence of TTX (n = 5) relative to control (right). *P < 0.05.