Table 4.
HRs for mineral levels and graft failure
| Mineral Level | Unadjusted HR (95% CI) | Adjusted HR (95% CI)a | Adjusted HR (95% CI)b |
|---|---|---|---|
| Calcium | |||
| Continuous per 0.40 mg/dl | 0.85 (0.71 to 1.03) | 0.83 (0.68 to 1.02) | 0.90 (0.74 to 1.09) |
| SD score, per SD score | 0.85 (0.70 to 1.03) | 0.83 (0.67 to 1.01) | 0.92 (0.76 to 1.12) |
| EPDWG targets | |||
| Below target | 2.25 (1.02 to 4.96)c | 2.45 (1.10 to 5.47)c | 1.50 (0.66 to 3.41) |
| Within target | 1.00 | 1.00 | 1.00 |
| Above target | 0.66 (0.26 to 1.67) | 0.63 (0.25 to 1.61) | 0.73 (0.29 to 1.85) |
| Phosphorus | |||
| Continuous per 0.30 mg/dl | 1.19 (1.07 to 1.32)c | 1.19 (1.07 to 1.33)c | 1.08 (0.96 to 1.20) |
| SD score, per SD score | 1.33 (1.12 to 1.60)c | 1.34 (1.12 to 1.60)c | 1.11 (0.93 to 1.33) |
| EPDWG targets | |||
| Below target | 0.76 (0.16 to 3.65) | 0.75 (0.16 to 3.61) | 0.67 (0.14 to 3.24) |
| Within target | 1.00 | 1.00 | 1.00 |
| Above target | 3.79 (1.96 to 7.33)c | 3.82 (1.97 to 7.42)c | 2.18 (1.10 to 4.32)c |
| PTH | |||
| Continuous per 10 pg/ml | 1.01 (1.00 to 1.02) | 1.01 (0.99 to 1.02) | 1.00 (0.98 to 1.01) |
| EPDWG targets | |||
| Below target | 7.76 (2.20 to 27.4)c | 10.3 (2.77 to 38.13)c | 2.14 (0.49 to 9.34) |
| Within target | 1.00 | 1.00 | 1.00 |
| Above target | 1.45 (0.52 to 4.01) | 1.44 (0.51 to 4.07) | 0.87 (0.27 to 2.74) |
EPDWG guidelines on prevention and treatment of renal osteodystrophy in children on chronic renal failure. HR, hazard ratio; 95% CI, 95% confidence interval; EPDWG, European Pediatric Dialysis Working Group; PTH, parathyroid hormone.
a
Adjusted for age, sex, and year of transplantation.
b
Adjusted for age, sex, eGFR, and year of transplantation.
c
Significantly different from 1.