Table 2.

Lithium physicochemical and toxicokinetic properties

Molecular mass	7 Da
Volume of distribution	0.7–0.9 L/kg
Protein binding	0%
Oral bioavailability	Immediate release: 95%–100%; modified release: 60%–90%
Therapeutic serum concentration	0.6–1.2 mEq/L
Half-life (therapeutic)	12–27 h
Conversion factor	1 mmol/L=1 mEq/L
Toxic dose (acute poisoning)	>1 g elemental Li