Table 3.
Comparison of left atrial volumetric indexes, strain (?) and strain rate (SR) parameters among patients with heart failure with preserved ejection fraction (HFpEF), patients with hypertrophic cardiomyopathy (HCM) and healthy controls
| P value | ||||||||
|---|---|---|---|---|---|---|---|---|
| HFpEF (n?=?10) | HCM (n?=?10) | Controls (n?=?10) | Overall | HCM vs. controls | HCM vs. HFpEF | HFpEF vs. control | ||
| Left atrial function | Left atrial volumetric index (%) | |||||||
| Reservoir | LAEF Total | 53.3 (6.7) | 59.4 (5.8) | 61.4 (6.0) | 0.028 | 0.290 | 0.070 | 0.013 |
| Conduit | LAEF Passive | 24.4 (4.3) | 25.6 (6.2) | 35.2 (8.8) | 0.010 | 0.019 | 0.705 | 0.005 |
| Booster pump | LAEF Booster | 29.0 (7.3) | 33.8 (5.7) | 26.2 (6.8) | 0.041 | 0.013 | 0.122 | 0.406 |
| Left atrial strain (%) | ||||||||
| Reservoir | ?s | 16.3 (5.8) | 22.1 (5.5) | 29.1 (5.3) | 0.001 | 0.008 | 0.034 | 0.001 |
| Conduit | ?e | 11.9 (4.0) | 10.4 (3.9) | 21.3 (5.1) | <0.001 | <0.001 | 0.650 | 0.001 |
| Booster pump | ?a | 4.5 (2.9) | 11.7 (4.0) | 7.8 (2.5) | 0.001 | 0.023 | 0.001 | 0.019 |
| Left atrial strain rate (s ?1 ) | ||||||||
| Reservoir | SRs | 0.8 (0.3) | 0.9 (0.2) | 1.1 (0.2) | 0.023 | 0.028 | 0.384 | 0.017 |
| Conduit | SRe | ?0.6 (0.1) | ?0.5 (0.2) | ?1.0 (0.3) | 0.002 | 0.002 | 0.733 | 0.003 |
| Booster pump | SRa | ?0.5 (0.2) | ?1.2 (0.4) | ?0.9 (0.3) | 0.004 | 0.131 | 0.004 | 0.010 |
| Left atrial volume (ml/m 2 ) | ||||||||
| LAV max | 53.1 (11.2) | 50.1 (13.6) | 34.8 (9.1) | 0.004 | 0.013 | 0.623 | 0.002 | |
| LAV min | 24.8 (6.3) | 20.6 (7.2) | 13.4 (4.2) | 0.002 | 0.021 | 0.186 | 0.001 | |
| LAV p-ac | 40.1 (7.9) | 37.7 (12.3) | 23.0 (7.7) | 0.002 | 0.011 | 0.597 | 0.001 | |
HFpEF, heart failure with preserved ejection fraction; HCM, hypertrophic cardiomyopathy; LAEF, left atrial emptying fraction; ?, strain; SR, strain rate; LAV max, maximum left atrial volume; LAV min, minimum left atrial volume; LAV p-ac, left atrial volume prior to atrial contraction. Bold p values indicate a significance level < 0.05.