Table 2.
Genotype and allele distribution of CCR 6- RNASET2 gene in AITDs patients, GD patients, HT patients, and controls
| SNP | Allele/ | P a | P b | P c | ||||
|---|---|---|---|---|---|---|---|---|
| Genotype | Controls | AITD | (OR, 95% CI) | GD | (OR, 95% CI) | HT | (OR, 95% CI) | |
| rs3093023 | GG | 329(36.9) | 341(33.4) | 0.252 | 224(33.3) | 0.242 | 117(33.4) | 0.428 |
| AG | 423(47.5) | 507(49.6) | 327(48.7) | 180(51.4) | ||||
| AA | 139(15.6) | 174(17.0) | 121(18.0) | 53(15.2) | ||||
| A | 701(39.3) | 855(41.8) | 0.118 | 569(42.3) | 0.091 | 286(40.9) | 0.486 | |
| G | 1081(60.7) | 1189(58.2) | 775(57.7) | 414(59.1) | ||||
| rs3093024 | GG | 328(36.9) | 341(33.4) | 0.264 | 224(33.4) | 0.253 | 117(33.4) | 0.430 |
| AG | 422(47.5) | 506(49.6) | 326(48.6) | 180(51.4) | ||||
| AA | 139(15.6) | 174(17.0) | 121(18.0) | 53(15.2) | ||||
| A | 700(39.4) | 854(41.8) | 0.124 | 568(42.3) | 0.096 | 286(40.9) | 0496 | |
| G | 1078(60.6) | 1188(58.2) | 774(57.7) | 414(59.1) | ||||
| rs6902119 | TT | 344(38.7) | 373(36.5) | 0.468 | 233(34.7) | 0.183 | 140(40.0) | 0.888 |
| CT | 420(47.2) | 487(47.7) | 327(48.7) | 160(45.7) | ||||
| CC | 126(14.1) | 162(15.8) | 112(16.6) | 50(14.3) | ||||
| C | 672(37.8) | 811(39.7) | 0.223 | 551(41.0) | 0.066 | 260(37.1) | 0.778 | |
| T | 1108(62.2) | 1233(60.3) | 793(59.0) | 440(62.9) | ||||
| rs9355610 | GG | 187(30.0) | 248(24.2) | 0.058 | 169(25.3) | 0.017 | 79(22.6) | 0.799 |
| AG | 448(50.3) | 520(51.1) | 345(51.7) | 175(50.0) | ||||
| AA | 256(19.7) | 249(24.7) | 153(23.0) | 96(27.4) | ||||
| G | 822(46.1) | 1016(49.9) | 0.018 | 683(51.2) | 0.005 | 333(47.6) | 0.516 | |
| 1.166(1.026-1.324) | 1.225(1.063-1.412) | |||||||
| A | 960(53.9) | 1018(50.1) | 651(48.8) | 367(52.4) |
Pa value, AITD versus Controls; Pb value, GD versus Controls; Pc value, HT versus Controls; OR, odd ratio; 95% CI, 95% confidence intervals.