Table 3.
Analysis of genotype and allele distribution of rs9355610 SNP in the GD patients and the controls after gender stratification
| SNP | Alleles/ | Controls | GD | HT | P a | P b | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| OR (95% CI) | OR (95% CI) | ||||||||||
| Genotypes | M (n = 298) | F (n = 593) | M (n = 205) | F (n = 462) | M (n = 43) | F (n = 307) | M | F | M | F | |
| rs9355610 | GG | 63(21.1) | 124(20.9) | 56(27.3) | 113(24.5) | 8(18.6) | 71(23.1) | 0.110 | 0.124 | 0.741 | 0.675 |
| AG | 148(49.7) | 300(50.6) | 104(50.7) | 241(52.2) | 20(46.5) | 155(50.5) | |||||
| AA | 87(29.2) | 169(28.5) | 45(22.0) | 108(23.3) | 15(34.9) | 81(26.4) | |||||
| G | 274(45.9) | 548(46.2) | 216(52.7) | 467(50.5) | 36(41.9) | 297(48.4) | 0.036 | 0.048 | 0.474 | 0.383 | |
| 1.308 | 1.19 | ||||||||||
| A | 322(54.1) | 638(53.8) | 194(47.3) | 457(49.5) | 50(58.1) | 317(51.6) | 1.017-1.684 | 1.001-1.413 | - | - | |
M, male; F, female; Pa value, GD versus Controls; Pb value, HT versus Controls; OR, odd ratio; 95% CI, 95% confidence intervals.