Figure 6.

Ingenuity pathway analysis of differentially regulated genes between CXCR3⁺ innate, CXCR3⁻ innate, and naive CD8⁺ T cells subsets. A) Functional pathway analysis of immune related gene interactions associated with cellular activation, differentiation, and cytotoxicity between innate CD8⁺ T-cell subsets. B) Functional pathway analysis of genes associated with 40S and 60S ribosomal subunits as well as others involved in translation initiation between innate CD8⁺ T-cell subsets. Genes in red are significantly up-regulated and genes in green are significantly down-regulated in CXCR3⁺ compared to CXCR3⁻ innate CD8⁺ T cells.